The plaque your stress test never saw
Dmitry Yaranov, MD, FACC
A normal stress test is one of the most reassuring sentences in medicine, and one of the most misunderstood.
The clearest look at this came from the PROSPECT study, published in 2011. Nearly 700 patients had all three coronary arteries imaged with intravascular ultrasound after an acute coronary syndrome, then were followed for about three years. About half of the later cardiac events traced not to the artery that had been treated but to other lesions, and on the original angiogram those lesions had looked only mildly narrowed, averaging about a third of the vessel diameter.1








